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<正>迷走神经刺激(VNS)已被美国食品药品监督管理局认定为对多种疾病的有效替代疗法,然而由于手术风险高、患者体内长期存在异物等诸多问题的存在妨碍了这一疗法的应用。经皮耳迷走神经刺激(taVNS)是由VNS发展而来的非侵入性、低成本的一种方法,以期替代植入式VNS,达到治疗疾病的目的。与传统针刺相比,taVNS可实现患者任意地点自行操作,同时由于其无创性,易于患者接受;与其他部位耳穴相比,taVNS通过刺激内脏代表区,可调节内脏功能。最初,taVNS仅仅被视为VNS治疗癫痫的替代疗法。
Abstract：[1]Kim AY,Marduy A,de Melo PS,Gianlorenco AC,Kim CK,Choi H,et al.Safety of transcutaneous auricular vagus nerve stimulation(taVNS):a systematic review and meta-analysis.Sci Rep 2022;12(1):22055.
[2]Wang Y,Li SY,Wang D,Wu MZ,He JK,Zhang JL,et al.Transcutaneous auricular vagus nerve stimulation:from concept to application.Neurosci Bull2021;37(6):853-62.
[3]Wang L,Wang Y,Wang YF,Zhang JL,Li SY,Wu MZ,et al.Transcutaneous auricular vagus nerve stimulators:a review of past,present,and future devices.Expert Rev Med Devices 2022;19(1):43-61.
[4]Krahl SE.Vagus nerve stimulation for epilepsy:a review of the peripheral mechanisms.Surg Neurol Int 2012;3(Suppl 1):S47-52.
[5]Clancy JA,Mary DA,Witte KK,Greenwood JP,Leuchars SA,Deuchars J.Non-invasive vagus nerve stimulation in healthy humans reduces sympathetic nerve activity.Brain Stimul 2014;7(6):871-7.
[6]Liu WH.Brief discussion on the broad-spectrum effect and specific effect of acupuncture-moxibustion.World J Acupunct-Moxibustion 2023;33(3):294-5.
基本信息:
中图分类号:R246
引用信息:
[1]张煜郑姮,邹凝怿,荣培晶,等.经皮耳迷走神经刺激:临床应用与机制[J].World Journal of Acupuncture-Moxibustion,2024,34(02):174-175+194-195.
基金信息:
Supported by Young Elite Scientists Sponsorship Program by CAST:2021-2023ZGZJXH-QNRC003; Beijing TCM Science and Technology Development Fund Project:BJZYON-2023-05; Fundamental Research Funds for the Central Public Welfare Research Institutes:ZZ202219002,ZZ-YQ2023006
2024-04-15
2024-04-15